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Dr. Valérie Chappe, PhD Assistant Dean, Graduate & Post-doctoral studies - Faculty of Medicine Atlantic Cystic Fibrosis Translational Research Group (Leader) Professor, Cystic Fibrosis Canada Researcher Phone: 902-494-2995 Email: valerie.chappe@dal.ca Associate Dean. 06/2021-present (Students & Postdocs)- Faculty of Graduate Studies, Dalhousie University. Halifax, NS, Canada. Professor. 06/2019 Department of Physiology & Biophysics, Dalhousie University - Faculty of Medicine, Halifax, NS, Canada. Assistant Dean. 01/2018-06/2021 Graduate & Post-doctoral studies, Dalhousie University - Faculty of Medicine, Halifax, NS, Canada. Associate Professor. 07/2010-06/2019 Department of Physiology & Biophysics, Dalhousie University - Faculty of Medicine, Halifax, NS, Canada. Assistant Professor.01/2005-03/2010 Department of Physiology & Biophysics, Dalhousie University - Faculty of Medicine, Halifax, NS, Canada. CIHR New Investigator In Cystic Fibrosis Basic Science. Post-Doctoral Fellow. 09/1999-12/2004. Department of Physiology, McGill University, Montreal, Qc, Canada. PhD in Cellular Biology. 07-1999. University Of Provence, Marseille, France. MSc in Cellular Biology, Molecular Biology & Microbiology - Major in Genetics & Development. 07/1996. University of Provence, Marseille, France. MSc, Major in Immunology. 07/1994. University of Aix-Marseille II, Marseille, France. BSc of Cellular Biology & Physiology. 07/1993. University of Aix-Marseille II, Marseille, France. |
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Frédéric Chappe Lab Manager, since 2005 Email: frederic.chappe@dal.ca |
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Félicie Lebref, MSc Visiting Research Graduate Student: January-June 2025 Home institution: University of Poitiers, France Project: Ex-vivo characterization of insulin release by pancreatic isslets from CF mice. Funding: MITAC Global Link Internship. |
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Daniel Neira Agonh, MSc MSc Student: 09/2023-07/2025 Project: Glucose intolerance and insulin resistance in CFRD mice. Funding: NSGS, DMRF. |
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Jonathan Bourgeois Experiental Learning & Volunteer. 3rd yr BSc student. 09/2024-12/2025 Honours thesis: Expression and localization of VPAC receptors in human lung tissues.. |
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Audrey Li Research Associate. 2015-2023 |
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Diogo Poroca Research Associate. 2019 |
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Dr. Mansong Li Research Associate. 2011-2013; 2018-2019 |
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Noha Amer Research Technician. 2010 |
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Nada Ismaiel Research Technician. 2009. |
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Sara Rafferty Research Technician. 2007. |
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Hemei Tang Research Technician. 2006-2008. |
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Will Lewis, MSc (2024) MSc Student: 09/2022-07/2024 Project: ACE2 and TMPRSS2 Expression and Localization in Cystic Fibrosis Lung: Potential Role in SARS-CoV2 susceptibility. Funding: DMRF award and Physiology Department entrance award. Current Position: Graduate Student, Assistant Physician Program, Dalhousie University. |
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Brett Allen, MSc (2022) MSc Student: 09/2021-09/2022 (Withdrawn for medical reasons) Project: VPAC receptors expression in CF lungs. Funding: Nova Scotia Graduate Sholarship. Physiology & Biophysics entrance award. Current Position: MD Dentistry Student, Dalhousie University. |
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Nazli Alizadeh-Tabrizi, MSc (2021) MSc Student: 09/2019-2021 (Co-supervisor with Dr Christian Lehmann) Project: The role of Iron chelation in pulmonary inflammation. Funding: NSGS Scholarship and Department of Physiology & Biophysics entrance award, Bader Scholarship. Current Position: Research Associate, Industry. |
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Poliana (Anna) Semaniakou, PhD (2020) PhD Student: 01/2016-12/2020 Project: Changes in Vasoactive Intestinal Peptide in Cystic Fibrosis. Funding: Faculty of Medicine Scholarship. Current Position: Project Lead, NS Health. 
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Maral Aali, PhD (2020) PhD Student: 05/2015-2020 (Co-supervisor with Dr Christian Lehmann) Project: Iron chelation in inflammation and infection. Funding: Killam scholarship. Current Position: MD resident. |
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Diogo daRocha Poroca, PhD (2019) PhD Student: 09/2013-08/2019 Project: Phosphorylation-dependent changes in the R-region interactions contribute to regulation of the CFTR chloride channel. Funding: Science Without Borders Scholarship - Brazil, NSGS. Current Position: Research Scientist, Industry. 
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Walaa Alshafie, MSc (2013) MSc Student 09/2011-12/2013 Project: Regulation of the CFTR protein by the Vasoactive Intestinal Peptide. Current Position: Research Associate. |
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Dustin Conrad, M.Sc (2011) Thesis: Stability and recycling mechanisms of the CFTR chloride channel in exocrine epithelia. Funding: NSERC PGM Award Current Position: MD, Practicing Physician. |
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Fanny Rousseau, MD/MSc (2010) 4th year visiting medical student. MD/MSc student 05/2010-07/2010. International Exchange Student from the University of Poitiers, France. Project: Isolation of mice tracheas and primary culture of epithelial cells for ex-vivo study of CFTR regulation by VIP. Funding: Studentship and travel allowance form the University of Poitiers. |
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Noha Amer, MSc (2010) MSc Student 01/2007-03/2010 Thesis: Serine 686 is critical for PKA-Induced Association of the R Domain with other regions of CFTR. Current Position: Research Assistant. |
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Nicole Alcolado, MSc (2010) MSc Student 05/2008-08/2010 Thesis:Regulation of CFTR membrane localization by Vasoactiva Intestinal Peptide (VIP). Funding: NSHRF Master Award. Current Position: MD, practicing Physician. |
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Nour Kandalaft Experiential Learning, 3rd yr BSc student. 01/2025-05/2025 Honours thesis: Isolation and culture of pancreatic islets. |
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Gabriella Dosman BSc Honours Med Sciences. 09/2024-05/2025 Honours thesis: Changes in glucagon level in mice with Cystic Fibrosis. (Co-supervisor) |
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Salma Khattab BSc Honours Med Sciences. 09/2024-05/2025 Honours thesis: Inflammation in the pancreas of mice with Cystic Fibrosis. (Co-supervisor) |
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Samantha Churchill BSc Honours Med Sciences. 09/2024-05/2025 Honours thesis: Insulin and glucagon level in Cystic Fibrosis and WT mice. |
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Samuel Farrell BSc Honours Med Sciences. 09/2024-05/2025 Honours thesis: L-cells distributions in the mice ileum. |
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Karolina Sadowska Summer Volunteer & BSc Honours Med Sciences. 2023 Honours thesis: Glucose intolerance in the CF mouse model of CFRD. |
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Anna Moris Summer Volunteer & BSc Med Sciences Honours/Capstone. 2023 |
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Chynea Drummond BSc Neuroscience Honours. 2022-2023 Honours thesis: ACE2 expression in different tissues affected by COVID-19. |
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Jamie Paton BSc Honours in Medical Sciences. Undergrad Volunteer and Honours thesis:Histological evaluation of Cystic Fibrosis progression in CF mice. |
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Sarah Brothers BSc. Med. Sci. Honours, 2017-2018 Honours thesis: Vasoactive Intestinal Peptide and Insulin concentration in CF and WT mice lung, pancreas and duodenum |
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Alina Cheng BSc Volunteer, 2016- |
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Grayson Gould BSc. Med. Sci. Honours, 2016- |
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Jennifer Wu BSc Volunteer, 2017- |
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Isobel MacKenzie BSc Honours, 01/2014-2016 Project: Establishing CF progression in patients with rare CFTR mutations. |
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Breagh Matheson BSc Honours, 04/2015 Thesis: Differences in VIP secretion between CF and Wildtype mice exoctine tissues. |
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Grace Jothiraj BSc Honours, 04/2015 Thesis: The mechanism by which VIP rescues F508del-CFTR in JME/CF15 cells. |
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Jiyoung Song BSc Honours, 05/2013-04/2014 Thesis: Characterization of mCFTR antibodies. |
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Andrew Kilby BSc Honours, 05/2013-04/2014 Thesis: Role of PKC phosphorylation in CFTR domains interaction. |
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Valerie Paquette BSc Honours, 2013/5 Thesis: The rare mutation P64L confers a dominant mild phenotype. |
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Patrick Boivert BSc Honors, 09/2011-04/2012 Thesis: Domain interactions in the CFTR chloride channel. Current position: Grad Student (McGill University) |
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Mehrsa Zahiremami Summer Research: 2014/2015 Project: CFTR expression & VIP secretion. |
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Marylin Min Ju Kwak Undergrade Volunteer, 06/2013-07/2013 Project: VIP-KO mice histology. |
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Shannon Vandriel Undergrade BSc Volunteer, 12/2011-05/2013 Project: Mapping of the mouse nasal cavity. |
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TianDia Gao International Medical Student. Summer research, 07-08/2012 Thesis: Histology of VIP-KO mice exocrine tissues. |
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Nada Ismaiel Summer Student, 05/2009-09/2009. Project: Establishing stable cell lines expressing recombinant mutated CFTR proteins. Current Position: Medical Student, Dalhousie Medical School. |
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Sara Rafferty Science Co-op & Honour Student. Biology Honours, Acadia University. Summer Studentship, 2007 & 2008. Honours Thesis(2008): ΔF508-CFTR stability at the apical membrane of human nasal epithelial cells. Funding: CCFF (Canadian Cystic Fibrosis Foundation) |
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Faiza Siddiqi Biology Honours. Honours Thesis(2008): P67L Mutated CFTR: Molecular Analysis of Cellular Localization and Phenotypic Analysis of Cystic Fibrosis Patients in the Maritimes. Funding: NSERC- USRA: Summer Award (2007). Current Position: Dentistry Student, Dalhousie University. |
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Mathew Kiberd Summer Student, 05-09/2006 Project: Regulation of wild-type and ΔF508-CFTR channels by PKC |
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Gage Seavilleklein Summer Student, 05-09/2006 Funding: NSERC-USRA. Summer award. 2006. Project: Characterization of the 7CA-CFTR Chloride Channel |